You have taken the wonderful concept of "naked apes" and added the word mutant. The question is, at what point did humans mutate, from what to what, AND was the mutation "random" or planned?
My money is that we have been mentally ill from the beginning due to our genesis and the cover-up of it. It explains so much. I also believe that we could become well, once the source of the trauma is identified, like PTSD. We all know how difficult it is to heal PTSD though. Hmmm, maybe that's why universe has decided to force the legalization of weed and mushrooms? To give us more of a chance. Of course that might just be a way to make the game more watch-able but hey... I'm in!